Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 4.011


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GABPAchr21_+_260291280.543.1e-02Click!
GABPB1chr15_-_48434567-0.421.0e-01Click!
ELK4chr1_-_203868622-0.194.9e-01Click!
ELK1chrX_-_47394937-0.068.1e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_50318801 4.864 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr8_+_30721208 4.255 NM_005671
UBXN8
UBX domain protein 8
chr1_+_20385164 4.128 NM_152376
UBXN10
UBX domain protein 10
chr12_-_53153639 3.891 NM_144594
GTSF1
gametocyte specific factor 1
chr12_-_53153613 3.850 GTSF1
gametocyte specific factor 1
chr12_+_118590039 3.673 NM_006253
PRKAB1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr9_-_133141726 3.600 NM_033387
FAM78A
family with sequence similarity 78, member A
chr2_+_113648036 3.463 PSD4
pleckstrin and Sec7 domain containing 4
chr6_-_28475478 3.401 NM_001163391
ZSCAN12
zinc finger and SCAN domain containing 12
chr19_+_17723285 3.391 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr3_+_47004457 3.306 NBEAL2
neurobeachin-like 2
chr6_-_31728447 3.299 NM_004639
NM_080702
NM_080703
BAG6


BCL2-associated athanogene 6


chr22_+_20350272 3.279 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chrX_-_153632355 3.230 NM_001081573
NM_080612
GAB3

GRB2-associated binding protein 3

chr15_+_72620570 3.215 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr2_+_169367345 3.073 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr5_+_82409072 3.054 NM_003401
NM_022406
NM_022550
XRCC4


X-ray repair complementing defective repair in Chinese hamster cells 4


chr10_-_43212681 3.036 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr6_-_33347563 2.951 NM_022553
VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr6_-_31728418 2.898 BAG6
BCL2-associated athanogene 6
chr16_+_29581783 2.879 NM_001030288
SPN
sialophorin
chr2_+_113648020 2.825 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr6_+_33347833 2.815 RPS18
ribosomal protein S18
chr6_-_31728405 2.768 BAG6
BCL2-associated athanogene 6
chr10_-_11976704 2.758 LOC219731
hypothetical LOC219731
chr6_+_30693464 2.757 NM_014046
MRPS18B
mitochondrial ribosomal protein S18B
chr7_-_128482354 2.733 TNPO3
transportin 3
chr5_+_87600485 2.730 LOC100505894
hypothetical LOC100505894
chr9_-_113977285 2.725 NM_022486
SUSD1
sushi domain containing 1
chr6_-_31728363 2.704 BAG6
BCL2-associated athanogene 6
chr16_-_30301357 2.663 SEPT1
septin 1
chr7_-_128482417 2.646 NM_001191028
NM_012470
TNPO3

transportin 3

chr8_-_68136881 2.642 COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chr1_-_1300680 2.626 NM_017900
AURKAIP1
aurora kinase A interacting protein 1
chr16_+_29582069 2.602 NM_003123
SPN
sialophorin
chr16_+_29582065 2.597 SPN
sialophorin
chr6_+_33347776 2.596 NM_022551
RPS18
ribosomal protein S18
chr6_-_31741545 2.584 GPANK1
G patch domain and ankyrin repeats 1
chr6_-_33375106 2.569 NM_004761
RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr5_+_87600596 2.568 LOC100505894
hypothetical LOC100505894
chr13_-_45654296 2.550 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_+_106293112 2.532 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_+_45926433 2.471 NM_016486
TMEM69
transmembrane protein 69
chr16_+_711139 2.420 NM_023933
FAM173A
family with sequence similarity 173, member A
chr7_+_106292932 2.416 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr9_+_263025 2.407 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr5_-_87600371 2.400 NM_153354
TMEM161B
transmembrane protein 161B
chr10_-_43212703 2.400 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr15_+_21361901 2.400 MKRN3
makorin ring finger protein 3
chr6_+_31741814 2.384 CSNK2B
casein kinase 2, beta polypeptide
chr2_+_32244406 2.349 NM_001193513
NM_001193514
NM_001193515
NM_017964
SLC30A6



solute carrier family 30 (zinc transporter), member 6



chr11_-_46678736 2.345 ARHGAP1
Rho GTPase activating protein 1
chr3_-_50353209 2.342 NM_007182
NM_170714
RASSF1

Ras association (RalGDS/AF-6) domain family member 1

chr7_+_106292975 2.340 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr3_-_9809357 2.327 NM_006354
NM_133480
TADA3

transcriptional adaptor 3

chr5_-_1687040 2.321 LOC728613
programmed cell death 6 pseudogene
chr11_-_72141064 2.297 NM_001040118
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr7_-_128482059 2.287 TNPO3
transportin 3
chr11_-_57038891 2.264 NM_001198810
SLC43A1
solute carrier family 43, member 1
chr1_-_220829704 2.235 NM_005681
NM_139352
TAF1A

TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa

chr4_-_140224794 2.231 ELF2
E74-like factor 2 (ets domain transcription factor)
chr17_-_3814334 2.230 NM_005173
NM_174953
NM_174954
NM_174955
NM_174956
NM_174957
NM_174958
ATP2A3






ATPase, Ca++ transporting, ubiquitous






chr6_-_33347417 2.228 VPS52
vacuolar protein sorting 52 homolog (S. cerevisiae)
chr17_+_35097851 2.201 NM_001005862
ERBB2
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr9_+_114288899 2.201 NM_133465
KIAA1958
KIAA1958
chr17_-_77244009 2.199 NM_001039842
C17orf90
chromosome 17 open reading frame 90
chr6_-_30692995 2.152 NM_002714
PPP1R10
protein phosphatase 1, regulatory (inhibitor) subunit 10
chr19_+_10402334 2.144 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr22_-_19543069 2.130 NM_058004
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr6_-_30693003 2.123 PPP1R10
protein phosphatase 1, regulatory (inhibitor) subunit 10
chr5_-_82409009 2.121 NM_174909
TMEM167A
transmembrane protein 167A
chr10_+_75174125 2.102 NM_004922
NM_198597
SEC24C

SEC24 family, member C (S. cerevisiae)

chr11_-_46678691 2.096 NM_004308
ARHGAP1
Rho GTPase activating protein 1
chr20_+_60395515 2.095 NM_001024
RPS21
ribosomal protein S21
chr10_+_75174151 2.090 SEC24C
SEC24 family, member C (S. cerevisiae)
chr19_+_17187154 2.080 NM_018467
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr9_+_114289178 2.076 KIAA1958
KIAA1958
chr1_+_164004789 2.058 LOC100147773
hypothetical LOC100147773
chr8_-_68137102 2.056 NM_006837
COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chr5_-_82408917 2.055 TMEM167A
transmembrane protein 167A
chr2_+_27659396 2.045 NM_032434
ZNF512
zinc finger protein 512
chr1_+_22224571 2.044 HSPC157
hypothetical LOC29092
chr19_+_17187196 2.032 USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr17_-_77244034 2.027 C17orf90
chromosome 17 open reading frame 90
chr17_-_35097792 2.018 NM_033419
PGAP3
post-GPI attachment to proteins 3
chr1_-_3702908 1.992 NM_020710
LRRC47
leucine rich repeat containing 47
chr9_-_85761451 1.947 C9orf64
chromosome 9 open reading frame 64
chr3_-_197549588 1.937 TM4SF19
transmembrane 4 L six family member 19
chr1_-_28842103 1.934 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr9_-_85761353 1.926 C9orf64
chromosome 9 open reading frame 64
chr13_-_45654327 1.924 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_-_46678715 1.915 ARHGAP1
Rho GTPase activating protein 1
chr1_-_164004611 1.915 TMCO1
transmembrane and coiled-coil domains 1
chr17_+_77244129 1.914 NM_199287
CCDC137
coiled-coil domain containing 137
chr9_-_85761472 1.909 NM_032307
C9orf64
chromosome 9 open reading frame 64
chr22_+_17799341 1.905 MRPL40
mitochondrial ribosomal protein L40
chr1_+_202752188 1.897 MDM4
Mdm4 p53 binding protein homolog (mouse)
chr6_-_31728121 1.893 NM_001098534
BAG6
BCL2-associated athanogene 6
chr3_-_197549640 1.892 NM_138461
TM4SF19
transmembrane 4 L six family member 19
chr21_+_32687282 1.886 C21orf119
chromosome 21 open reading frame 119
chr17_+_7682355 1.885


chr22_+_19543248 1.883 NM_004782
SNAP29
synaptosomal-associated protein, 29kDa
chr9_+_130124566 1.880 NM_016035
COQ4
coenzyme Q4 homolog (S. cerevisiae)
chr3_+_9809776 1.877 NM_001198780
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr9_+_130124873 1.876 COQ4
coenzyme Q4 homolog (S. cerevisiae)
chr1_+_202752084 1.873 NM_002393
MDM4
Mdm4 p53 binding protein homolog (mouse)
chr1_-_164004730 1.873 NM_019026
TMCO1
transmembrane and coiled-coil domains 1
chr16_-_30301634 1.866 NM_052838
SEPT1
septin 1
chr6_-_32268267 1.855 GPSM3
G-protein signaling modulator 3
chr6_+_43711566 1.842 MAD2L1BP
MAD2L1 binding protein
chr2_+_65308332 1.840 NM_001005386
NM_005722
ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr15_-_81216179 1.837


chr7_+_6583560 1.835 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr11_-_9292737 1.828 NM_001165030
NM_015012
TMEM41B

transmembrane protein 41B

chr15_-_64577122 1.808 NM_006049
SNAPC5
small nuclear RNA activating complex, polypeptide 5, 19kDa
chr1_+_209622781 1.797 C1orf97
chromosome 1 open reading frame 97
chr6_+_43711532 1.774 NM_014628
MAD2L1BP
MAD2L1 binding protein
chr15_+_89274413 1.770 NM_001039675
UNC45A
unc-45 homolog A (C. elegans)
chr22_-_19543012 1.768 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr11_-_57054756 1.766 NM_012456
TIMM10
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr6_-_33398656 1.758 NM_001141969
NM_001141970
NM_001350
DAXX


death-domain associated protein


chr9_-_130124820 1.757 TRUB2
TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr1_+_209622764 1.755 C1orf97
chromosome 1 open reading frame 97
chrX_-_130792297 1.754 LOC286467
hypothetical LOC286467
chr6_+_31741635 1.740 NM_001320
CSNK2B
casein kinase 2, beta polypeptide
chr11_-_66925875 1.720 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr3_+_154035425 1.719 NM_002563
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr19_-_1430198 1.717 NM_152482
C19orf25
chromosome 19 open reading frame 25
chr10_-_43212166 1.716 NM_001098208
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr4_-_140224914 1.701 NM_006874
ELF2
E74-like factor 2 (ets domain transcription factor)
chr21_-_37260488 1.700 HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr22_-_19543099 1.699 PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr11_+_63412562 1.690 NM_017490
MARK2
MAP/microtubule affinity-regulating kinase 2
chr7_-_91713044 1.687 NM_004912
NM_001013406
NM_194454
KRIT1


KRIT1, ankyrin repeat containing


chr3_+_9379706 1.679 NM_001114092
NM_015453
THUMPD3

THUMP domain containing 3

chr13_-_45654292 1.678 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_+_68353738 1.676 NM_007014
NM_199423
WWP2

WW domain containing E3 ubiquitin protein ligase 2

chr22_-_18484428 1.670 TRMT2A
TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr17_-_30929669 1.670 NM_000286
PEX12
peroxisomal biogenesis factor 12
chr21_+_44109454 1.660 AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chrX_+_109132507 1.655 NM_017698
TMEM164
transmembrane protein 164
chr9_-_130124317 1.648 NM_015679
TRUB2
TruB pseudouridine (psi) synthase homolog 2 (E. coli)
chr21_+_44109529 1.648 NM_020132
AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr19_-_1430194 1.645 C19orf25
chromosome 19 open reading frame 25
chr8_-_68136700 1.633 COPS5
COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
chr5_-_1687099 1.626 LOC728613
programmed cell death 6 pseudogene
chr12_-_46785682 1.616 NM_014554
SENP1
SUMO1/sentrin specific peptidase 1
chr2_+_201462294 1.614 NM_001136039
NM_001142355
NM_021824
NIF3L1


NIF3 NGG1 interacting factor 3-like 1 (S. pombe)


chr11_-_9292694 1.609 TMEM41B
transmembrane protein 41B
chr9_+_70509925 1.609 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr5_+_177490582 1.606 RMND5B
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr11_-_118394242 1.606 NM_001028
RPS25
ribosomal protein S25
chr1_-_38228179 1.604 NM_006802
SF3A3
splicing factor 3a, subunit 3, 60kDa
chr22_+_19543350 1.601 SNAP29
synaptosomal-associated protein, 29kDa
chr5_-_40871040 1.598 RPL37
SNORD72
ribosomal protein L37
small nucleolar RNA, C/D box 72
chr1_+_36169260 1.594 NM_024852
NM_177422
EIF2C3

eukaryotic translation initiation factor 2C, 3

chr19_+_19487535 1.591 NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr7_+_120416680 1.590 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr5_+_177490654 1.588 RMND5B
required for meiotic nuclear division 5 homolog B (S. cerevisiae)
chr11_+_65384513 1.585 MUS81
MUS81 endonuclease homolog (S. cerevisiae)
chr7_+_149651202 1.582 NM_001142928
NM_023942
LRRC61

leucine rich repeat containing 61

chr6_+_42955353 1.578 RPL7L1
ribosomal protein L7-like 1
chr22_+_18091065 1.573 NM_000407
GP1BB
glycoprotein Ib (platelet), beta polypeptide
chr5_+_131920455 1.568 NM_005732
RAD50
RAD50 homolog (S. cerevisiae)
chr15_+_41880074 1.567 C15orf63
chromosome 15 open reading frame 63
chr5_-_40871082 1.562 NM_000997
RPL37
ribosomal protein L37
chr17_-_55824359 1.560 NM_032582
USP32
ubiquitin specific peptidase 32
chr17_-_1499849 1.560 NM_031430
RILP
Rab interacting lysosomal protein
chr11_-_64269501 1.560 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr17_-_38530830 1.557 BRCA1
breast cancer 1, early onset
chr7_+_149651481 1.551 LRRC61
leucine rich repeat containing 61
chr19_+_40831061 1.550 COX6B1
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
chr6_-_31618203 1.549 NM_004640
NM_080598
DDX39B

DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B

chr19_-_1430116 1.542 C19orf25
chromosome 19 open reading frame 25
chr11_+_384199 1.537 NM_007183
PKP3
plakophilin 3
chr12_-_54607154 1.532 NM_001143853
WIBG
within bgcn homolog (Drosophila)
chr1_+_28867801 1.527 NM_006582
NM_024482
GMEB1

glucocorticoid modulatory element binding protein 1

chr2_+_241156776 1.526 NM_018226
RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr11_+_118394350 1.524 NM_016146
TRAPPC4
trafficking protein particle complex 4
chr2_-_201461945 1.522 NM_032472
NM_130906
PPIL3

peptidylprolyl isomerase (cyclophilin)-like 3

chr20_+_60311443 1.520 ADRM1
adhesion regulating molecule 1
chr6_+_32034767 1.515 SKIV2L
superkiller viralicidic activity 2-like (S. cerevisiae)
chr22_-_17798998 1.511 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr2_-_73817935 1.505 NM_016058
TPRKB
TP53RK binding protein
chr7_-_72063147 1.504 NSUN5P2
NOP2/Sun domain family, member 5 pseudogene 2
chr11_+_384238 1.503 PKP3
plakophilin 3
chr19_-_61324412 1.502 ZNF787
zinc finger protein 787
chr22_-_17799177 1.498 HIRA
HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
chr6_-_31617704 1.494 DDX39B
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
chr16_-_1999760 1.494 NM_178167
ZNF598
zinc finger protein 598
chr11_-_66961709 1.490 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr17_-_44058612 1.484 NM_024017
HOXB9
homeobox B9
chr16_+_68353662 1.484 WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr9_-_137992766 1.477 UBAC1
UBA domain containing 1
chr11_-_67795903 1.477 C11orf24
chromosome 11 open reading frame 24
chr5_-_945613 1.477 NM_001009877
BRD9
bromodomain containing 9
chr19_+_52544377 1.476 NM_014681
DHX34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr2_-_96334996 1.472 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr17_+_33761234 1.470 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr17_+_46585953 1.468 NME1
NME1-NME2
non-metastatic cells 1, protein (NM23A) expressed in
NME1-NME2 readthrough

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.48 1.25e-35 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 3.39e-34 GO:0044260 cellular macromolecule metabolic process
1.54 6.66e-34 GO:0090304 nucleic acid metabolic process
1.55 6.46e-27 GO:0016070 RNA metabolic process
1.28 1.28e-26 GO:0043170 macromolecule metabolic process
1.37 1.91e-24 GO:0034641 cellular nitrogen compound metabolic process
1.50 8.24e-24 GO:0010467 gene expression
1.22 1.37e-22 GO:0044237 cellular metabolic process
1.34 4.07e-22 GO:0006807 nitrogen compound metabolic process
2.06 1.11e-20 GO:0016032 viral reproduction
1.47 5.21e-18 GO:0034645 cellular macromolecule biosynthetic process
1.46 8.00e-18 GO:0009059 macromolecule biosynthetic process
1.77 1.77e-17 GO:0006396 RNA processing
1.19 3.42e-17 GO:0044238 primary metabolic process
1.85 3.43e-17 GO:0016071 mRNA metabolic process
1.17 2.37e-16 GO:0008152 metabolic process
2.32 3.52e-15 GO:0000375 RNA splicing, via transesterification reactions
2.34 4.78e-15 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.34 4.78e-15 GO:0000398 nuclear mRNA splicing, via spliceosome
1.32 1.58e-14 GO:0071841 cellular component organization or biogenesis at cellular level
1.89 1.70e-13 GO:0006397 mRNA processing
1.98 1.94e-12 GO:0008380 RNA splicing
1.31 3.67e-12 GO:0044267 cellular protein metabolic process
1.25 9.25e-12 GO:0071840 cellular component organization or biogenesis
1.92 3.53e-11 GO:0006412 translation
1.30 3.91e-11 GO:0044249 cellular biosynthetic process
1.09 1.05e-10 GO:0009987 cellular process
2.14 1.10e-10 GO:0022613 ribonucleoprotein complex biogenesis
1.29 1.87e-10 GO:0009058 biosynthetic process
1.37 1.91e-10 GO:0006996 organelle organization
1.28 2.56e-10 GO:0071842 cellular component organization at cellular level
2.08 4.99e-10 GO:0071843 cellular component biogenesis at cellular level
2.69 1.32e-09 GO:0019080 viral genome expression
2.69 1.32e-09 GO:0019083 viral transcription
2.53 1.61e-09 GO:0006414 translational elongation
1.61 4.50e-09 GO:0000278 mitotic cell cycle
1.45 4.53e-09 GO:0007049 cell cycle
2.59 8.48e-09 GO:0006415 translational termination
2.49 1.52e-08 GO:0043241 protein complex disassembly
2.49 1.52e-08 GO:0043624 cellular protein complex disassembly
2.24 2.01e-08 GO:0019058 viral infectious cycle
1.22 3.59e-08 GO:0016043 cellular component organization
2.28 3.95e-08 GO:0042254 ribosome biogenesis
1.43 7.56e-08 GO:0032774 RNA biosynthetic process
1.61 7.78e-08 GO:0006974 response to DNA damage stimulus
2.34 1.02e-07 GO:0032984 macromolecular complex disassembly
2.34 1.02e-07 GO:0034623 cellular macromolecular complex disassembly
1.47 1.85e-07 GO:0022402 cell cycle process
1.55 2.31e-07 GO:0006259 DNA metabolic process
2.07 3.40e-07 GO:0022415 viral reproductive process
1.50 4.28e-07 GO:0022403 cell cycle phase
1.22 6.14e-07 GO:0019538 protein metabolic process
1.87 1.38e-06 GO:0071156 regulation of cell cycle arrest
1.74 1.88e-06 GO:0051329 interphase of mitotic cell cycle
1.72 2.75e-06 GO:0051325 interphase
1.68 3.16e-06 GO:0010564 regulation of cell cycle process
1.54 4.18e-06 GO:0044265 cellular macromolecule catabolic process
1.85 5.73e-06 GO:0000075 cell cycle checkpoint
1.49 7.45e-06 GO:0009057 macromolecule catabolic process
1.55 9.43e-06 GO:0034621 cellular macromolecular complex subunit organization
1.74 1.37e-05 GO:0034660 ncRNA metabolic process
2.12 1.65e-05 GO:0031018 endocrine pancreas development
2.01 2.06e-05 GO:0031016 pancreas development
1.46 5.85e-05 GO:0051726 regulation of cell cycle
1.40 7.32e-05 GO:0046907 intracellular transport
1.59 9.90e-05 GO:0016568 chromatin modification
2.22 1.04e-04 GO:0006364 rRNA processing
1.83 1.11e-04 GO:0034470 ncRNA processing
1.68 1.44e-04 GO:0007346 regulation of mitotic cell cycle
1.38 2.05e-04 GO:0043933 macromolecular complex subunit organization
2.28 2.07e-04 GO:0000216 M/G1 transition of mitotic cell cycle
2.06 2.36e-04 GO:0000084 S phase of mitotic cell cycle
2.15 2.43e-04 GO:0016072 rRNA metabolic process
1.79 3.78e-04 GO:0022411 cellular component disassembly
1.79 3.78e-04 GO:0071845 cellular component disassembly at cellular level
1.44 4.50e-04 GO:0071822 protein complex subunit organization
2.03 4.79e-04 GO:0051320 S phase
1.58 5.49e-04 GO:0006281 DNA repair
1.90 5.81e-04 GO:0000082 G1/S transition of mitotic cell cycle
1.30 6.59e-04 GO:0044248 cellular catabolic process
1.42 6.80e-04 GO:0051276 chromosome organization
1.29 1.16e-03 GO:0044085 cellular component biogenesis
1.35 1.49e-03 GO:0033554 cellular response to stress
2.21 1.60e-03 GO:0006353 transcription termination, DNA-dependent
1.75 2.22e-03 GO:0006260 DNA replication
2.28 3.21e-03 GO:0071158 positive regulation of cell cycle arrest
2.09 3.61e-03 GO:0071826 ribonucleoprotein complex subunit organization
2.16 3.63e-03 GO:0006354 transcription elongation, DNA-dependent
2.11 3.64e-03 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.10 5.36e-03 GO:0022618 ribonucleoprotein complex assembly
1.87 5.39e-03 GO:0007093 mitotic cell cycle checkpoint
1.25 6.02e-03 GO:0009056 catabolic process
2.10 7.88e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
2.10 7.88e-03 GO:0071779 G1/S transition checkpoint
1.89 9.49e-03 GO:0031570 DNA integrity checkpoint
1.28 1.01e-02 GO:0008104 protein localization
1.67 1.03e-02 GO:0006457 protein folding
2.24 1.09e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.24 1.09e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.24 1.09e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.24 1.09e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.24 1.09e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.24 1.09e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
2.24 1.09e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.24 1.09e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
2.17 1.15e-02 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.59 1.16e-02 GO:0009166 nucleotide catabolic process
2.15 1.17e-02 GO:0006302 double-strand break repair
1.15 1.27e-02 GO:0060255 regulation of macromolecule metabolic process
1.69 1.51e-02 GO:0016569 covalent chromatin modification
2.14 1.72e-02 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
2.14 1.72e-02 GO:0072594 establishment of protein localization to organelle
1.70 2.03e-02 GO:0043687 post-translational protein modification
1.89 2.09e-02 GO:0000077 DNA damage checkpoint
1.52 2.28e-02 GO:0048285 organelle fission
1.25 2.44e-02 GO:0051641 cellular localization
2.06 2.46e-02 GO:0031123 RNA 3'-end processing
1.58 2.67e-02 GO:0006195 purine nucleotide catabolic process
1.70 3.42e-02 GO:0006417 regulation of translation
1.16 3.48e-02 GO:0010468 regulation of gene expression
1.51 3.53e-02 GO:0000087 M phase of mitotic cell cycle
1.30 3.54e-02 GO:0006351 transcription, DNA-dependent
1.67 3.56e-02 GO:0016570 histone modification
1.24 3.62e-02 GO:0033036 macromolecule localization
2.08 3.69e-02 GO:0051352 negative regulation of ligase activity
2.08 3.69e-02 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.56 4.15e-02 GO:0072523 purine-containing compound catabolic process
1.75 4.17e-02 GO:0006310 DNA recombination
1.13 4.35e-02 GO:0031323 regulation of cellular metabolic process
1.39 4.57e-02 GO:0006753 nucleoside phosphate metabolic process
1.39 4.57e-02 GO:0009117 nucleotide metabolic process
1.59 4.57e-02 GO:0009261 ribonucleotide catabolic process
1.99 4.77e-02 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.01 4.97e-02 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.16 1.61e-48 GO:0044424 intracellular part
1.16 8.55e-48 GO:0005622 intracellular
1.19 1.42e-43 GO:0043229 intracellular organelle
1.19 3.08e-43 GO:0043226 organelle
1.21 9.98e-41 GO:0043227 membrane-bounded organelle
1.21 1.70e-40 GO:0043231 intracellular membrane-bounded organelle
1.52 2.57e-35 GO:0070013 intracellular organelle lumen
1.51 1.31e-34 GO:0031974 membrane-enclosed lumen
1.29 1.86e-34 GO:0044446 intracellular organelle part
1.53 3.20e-34 GO:0044428 nuclear part
1.28 7.04e-34 GO:0044422 organelle part
1.50 1.53e-33 GO:0043233 organelle lumen
1.56 6.94e-32 GO:0031981 nuclear lumen
1.27 2.08e-31 GO:0005634 nucleus
2.11 8.69e-31 GO:0030529 ribonucleoprotein complex
1.31 1.64e-21 GO:0032991 macromolecular complex
1.16 7.03e-20 GO:0005737 cytoplasm
1.35 1.89e-19 GO:0043228 non-membrane-bounded organelle
1.35 1.89e-19 GO:0043232 intracellular non-membrane-bounded organelle
1.52 3.61e-19 GO:0005654 nucleoplasm
1.19 2.53e-16 GO:0044444 cytoplasmic part
1.76 4.80e-14 GO:0005730 nucleolus
1.33 1.21e-12 GO:0005829 cytosol
2.14 3.98e-11 GO:0005840 ribosome
2.29 4.07e-10 GO:0005681 spliceosomal complex
2.59 1.13e-08 GO:0071013 catalytic step 2 spliceosome
1.04 5.00e-08 GO:0005623 cell
1.04 6.73e-08 GO:0044464 cell part
2.04 2.47e-07 GO:0044445 cytosolic part
2.52 2.87e-07 GO:0022626 cytosolic ribosome
1.45 5.22e-07 GO:0044451 nucleoplasm part
1.20 9.41e-07 GO:0043234 protein complex
2.46 3.15e-05 GO:0015934 large ribosomal subunit
1.72 5.64e-05 GO:0016604 nuclear body
1.45 5.95e-05 GO:0005694 chromosome
2.71 6.32e-04 GO:0022625 cytosolic large ribosomal subunit
2.32 2.42e-03 GO:0015935 small ribosomal subunit
1.42 2.94e-03 GO:0044427 chromosomal part
1.34 3.54e-03 GO:0044429 mitochondrial part
2.06 4.11e-03 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
1.23 7.59e-03 GO:0005739 mitochondrion
2.64 9.87e-03 GO:0030532 small nuclear ribonucleoprotein complex
1.31 1.02e-02 GO:0031967 organelle envelope
2.54 1.22e-02 GO:0022627 cytosolic small ribosomal subunit
1.30 1.50e-02 GO:0031975 envelope
3.72 2.87e-02 GO:0005732 small nucleolar ribonucleoprotein complex
1.25 3.47e-02 GO:0005794 Golgi apparatus
1.16 4.06e-02 GO:0031090 organelle membrane
1.72 4.07e-02 GO:0016607 nuclear speck

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 7.07e-23 GO:0005515 protein binding
1.29 1.92e-17 GO:0003676 nucleic acid binding
1.65 2.35e-17 GO:0003723 RNA binding
1.09 2.82e-14 GO:0005488 binding
2.21 8.63e-10 GO:0003735 structural constituent of ribosome
1.91 6.87e-06 GO:0008168 methyltransferase activity
1.85 2.93e-05 GO:0016741 transferase activity, transferring one-carbon groups
1.22 3.06e-05 GO:0000166 nucleotide binding
1.19 2.63e-03 GO:0008270 zinc ion binding
1.18 3.12e-03 GO:0003677 DNA binding
1.19 1.00e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.19 1.08e-02 GO:0017076 purine nucleotide binding
1.19 1.65e-02 GO:0032553 ribonucleotide binding
1.19 1.65e-02 GO:0032555 purine ribonucleotide binding
1.10 2.89e-02 GO:0003824 catalytic activity